Conclusions: MDMA is the major active drug in ecstasy pills, but there is a high degree of variation in doses. Use of multiple pills over the course of one session is common and results in a sustained increase in MDMA plasma concentrations over a number of hours.
This is likely to lead to a much greater exposure of the brain to MDMA than would be predicted from controlled single-dose pharmacokinetic studies. Research results vary on whether MDMA is addictive. MDMA was first used in the s as an aid in psychotherapy mental disorder treatment using "talk therapy".
The drug did not have the support of clinical trials studies using humans or approval from the U. In , The U. However, some researchers remain interested in its value in psychotherapy when given to patients under carefully controlled conditions. MDMA is currently in clinical trials as a possible treatment aid for post-traumatic stress disorder PTSD ; for anxiety in terminally ill patients; and for social anxiety in autistic adults.
There are no specific medical treatments for MDMA addiction. Some people seeking treatment for MDMA addiction have found behavioral therapy to be helpful. Scientists need more research to determine how effective this treatment option is for addiction to MDMA.
This publication is available for your use and may be reproduced in its entirety without permission from NIDA. Department of Health and Human Services. National Institutes of Health. Drug Topics. Bronze This resource has undergone expert review. Resource Overview Year: Year 9—10, Year 11— Time Allocated Partial lesson under 45mins.
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